SERVICES Offered by in-ADME Research

Visiting a Beijing organizaton, Oct 2008. (c) Copyright 2008 by A. Avdeef.

in-ADME Research provides consulting services in PHYSICOCHEMICAL PROFILING (solubility, dissolution, permeability, pK_a/pH) applied to drug discovery and early development.

Expert Witness Support

The Principal Consultant (116 publications, 4 books, 6 patents) recent client requests:

• patent litigation between two large pharmaceutical companies, with in-ADME Research offering unique & deep knowledge of pH & pK_a measurement applied to drugs
• litigation focusing on salt solubility of drugs
• metal binding in consumer products litigation 

If your Expert Witness needs can take advantage of in-ADME Research’s core expertise, we might be able to help and would like to discuss this with you.

Consultancy

To add value to the client’s drug discovery and early development projects, in-ADME Research can consult with the client to improve cell-based/PAMPA & mechanistic dissolution assays to the prediction of human intestinal absorption, blood-brain barrier permeability, & unbound-drug brain exposure.

Prof. Norman Ho asking a question at PAMPA2002, San Francisco, Jul 2002. (c) Copyright 2002 by A. Avdeef.